About Us Network for health research
The OneFlorida+ Clinical Research Network is a collaboration among researchers, clinicians and patients.

Who We Are
The OneFlorida+ Clinical Research Network is a collaboration among researchers, clinicians and patients in Florida, Georgia, Alabama, Arkansas, California and Minnesota along with six affiliated health systems and practices to create an enduring infrastructure for a wide range of health research, including pragmatic clinical trials, comparative effectiveness research, implementation science studies, observational research, and cohort discovery.

Network Partners
Network partners include universities, public and private health care systems, and state agencies. Current partners include:
- University of Florida
- Florida State University
- University of Miami
- University of South Florida
- Emory University in Atlanta
- University of Alabama at Birmingham
- University of Arkansas
- University of California, Irvine
- University of Minnesota
- six universities’ affiliated health systems and practices
- AdventHealth (Orlando)
- Tallahassee Memorial HealthCare
- Tampa General Hospital
- Bond Community Health (Tallahassee)
- Community Health IT (Kennedy Space Center)
- Nicklaus Children’s Hospital (Miami)
- Jackson Health System (Miami)
- Capital Health Plan (Tallahassee)
- Bendcare (Boca Raton)
- Florida Agency for Health Care Administration, which oversees the Florida Medicaid Program
OneFlorida+ partners are committed to conducting stakeholder-engaged research in partnership with health systems, clinicians, patients, payers, policymakers and communities. Our partners strive for efficiency, offering multiple approaches and tools to facilitate healthcare research for today’s complex health issues. OneFlorida+ network partners also ensure that lessons from research conducted in diverse settings are systematically captured and translated back into improved health, health care and health policy.
What We Do
The OneFlorida+ Clinical Research Network unites researchers, clinicians, patients and stakeholders to address some of the nation’s biggest health challenges, and it serves as a central data resource for improving health, health care and health policy.
Together, OneFlorida+ partners provide health care to more than 26.4 million patients throughout Florida, Atlanta, Georgia; Birmingham, Alabama; Arkansas; Minnesota; and Irvine, California. To support research aimed at addressing the country’s most pressing healthcare needs, OneFlorida+’s research infrastructure allows investigators to:
- Identify cohorts and conduct observational research using aggregate and limited patient-level health data from diverse partners across the Southeast
- Identify and intervene with patients at the point of care
- Conduct pragmatic clinical trials and other interventional studies in eligible, research-ready clinics, including implementation science and comparative effectiveness research.
The Data Trust
The OneFlorida+ Data Trust’s regional repository of healthcare data is regularly updated with the inclusion of new partners and data refreshes from existing partners. All data are cleaned, transformed, curated and contained in a centralized data warehouse, allowing streamlined inquiries and uniform results based on high-quality data. Legal agreements for data use and use of OneFlorida+’s centralized IRB have already been negotiated with all partners, reducing paperwork and the administrative burden.
Scientists and clinicians rely on the OneFlorida+ Data Trust to support a variety of research activities, including hypothesis generation, cohort discovery, prep-to-research activities, participant enrollment, observational studies, research workflow (such as informed consent and eligibility determination), and study data collection.
The Clinical Research Network
The OneFlorida+ Clinical Research Network (CRN) allows researchers to conduct pragmatic clinical trials and other interventional studies in the network’s research-ready clinics. Research is conducted in real-world settings to promote the implementation of evidence-based healthcare practices into patient care.
Intervention sites include academic health care centers and affiliated clinics, private health systems and clinics, public health care systems and clinics, community health centers, and physician-owned practices.
ENGAGEMENT
Engaging community scientists and other stakeholders in health research can provide the study team with valuable insights and different perspectives that increase the usefulness, usability and accessibility of study findings. Our researchers routinely confer with a variety of stakeholders to strengthen our resources and infrastructure and improve health research.
OneFlorida+
Community Scientists
Community members with an interest in health research may apply to join the OneFlorida+ Community Scientist program. After undergoing a brief training to familiarize them with health research, community scientists work alongside scientists as consultants and collaborators, offering lay perspectives and insights on everything from the study aims to participant recruiting to the dissemination of the study findings.

OneFlorida+
Health System Leaders
We engage CEOs, chief operating officers, chief medical officers and other health system leaders through annual individual in-person meetings to leverage their expertise. We also provide ongoing support to them for transmission of electronic health record data to the OneFlorida+ Data Trust and for submitting additional data elements to allow for more robust studies, such as additional lab data or Apgar scores.

Oneflorida+
Clinicians
We identify and work with recognized physician leaders in communities throughout the network to help develop recruiting practices for study participation. Clinicians who participate in studies also have access to the OneFlorida+ Maintenance of Certification (MOC) Program, an important engagement tool that contributes to the sustainability of an intervention after research completion.

GOVERNANCE
The network is governed by the OneFlorida+ Executive Committee, which adopted a partnership governance model and includes representatives from all partners. The committee oversees the development and utilization of the network’s infrastructure cores as well as research alliances created among network partners.
One Florida+ Executive Committee Co-Chairs
Executive committee co-chair
Elizabeth Shenkman, PhD
Co-director of the University of Florida Clinical and Translational Science Institute (UF CTSI)

Executive committee co-chair
Mei Liu, PhD
Director of predictive analytics for UF HOBI, and associate professor of HOBI

Executive committee co-chair
Mike Mugavero, MD.
Associate Dean for clinical and translation research at University of Alabama at Birmingham
