Data for health

OneFlorida+ Clinical Research Network

The OneFlorida+ Clinical Research Network is a central resource for large-scale health care data and research support. It unites researchers, clinicians, patients and stakeholders to address some of today’s biggest health challenges. The network’s many academic institutions and health systems provide care for tens of millions of patients, creating a dynamic resource to facilitate health care research and improve health, health care and health policy.

Poster presentation at conference

Our Mission: Improving Health Care

Our access to large data sets is exceptional.

26 Million Patients

+10,000 Health Care Providers

+1,000 Practices and Clinics

72 Hospitals

new website

Visit each section of the website using the links below. This updated website was launched in 2025.

About

The OneFlorida+ Clinical Research Network is a collaboration among researchers, clinicians and patients.

Research

OneFlorida+’s diverse and aging population is representative of the America of tomorrow.

Data

The OneFlorida+ Data Trust is a repository of health-care data from Florida and select states.

News & Events

Learn about some of our innovative efforts and accomplishments.

Contact

Connect with the Coordinating Center for the OneFlorida+ Clinical Research Network.

network News

Study finds COVID-19 mRNA vaccine sparks immune…

Patients with advanced lung or skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly…

Person in white coat holds Syringe

National Academies report cites OneFlorida+ role…

Elizabeth Shenkman, Ph.D. Following a public workshop in July 2024, a report from the National Academies of Sciences, Engineering, and Medicine…

Report from National Academies of Sciences, Engineering, and Medicine.

Rediscover the “plus” in OneFlorida+ Clinical…

“The growth that we have experienced in OneFlorida+ has been incredible,” says Brittney Roth Manning, the Director of Research and Operations…

Poster presentation at conference
UF supercomputer

The OneFlorida+ Clinical Research Network is a Clinical Research Network in PCORnet® which has been developed with funding from the Patient-Centered Outcomes Research Institute® (PCORI®). The OneFlorida+ Clinical Research Network’s participation in PCORnet is partially funded through PCORI Award (RI-FLORIDA-01-PS8).